Mannogem XL Opal is spray-dried mannitol that provides superior binding properties and tablet ability over standard 160 µm spray-dried mannitols and other excipients. ideal for use with moisture-sensitive APIs.
Mannogem® XL Opal
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Supplier: SPI Pharma
Product Applications: Chewable Tablet, DC Tablet, Oral Modified Drug Release Systems (MUP, ER), Orally Disintegrating Tablet (ODT), Soft-Chews, Tablet,
Product Class: Binder, Excipient,
Product Categories: Nutraceutical, Pharmaceutical
Supplier: SPI Pharma
Product Applications: Chewable Tablet, DC Tablet, Oral Modified Drug Release Systems (MUP, ER), Orally Disintegrating Tablet (ODT), Soft-Chews, Tablet,
Product Class: Binder, Excipient,
Product Categories: Nutraceutical, Pharmaceutical
Mannogem® XL Opal
Product Information
Mannogem XL Opal is spray-dried grade Mannitol (160 µm). It is the highest of all compressibility products with a good general particle size for mixing with API’s and other ingredients. Mannogem XL Opal allows for formulation simplification; smaller tablets; improved patient convenience.
Quick Benefits Glance:
- Highest compressibility grade and high flowability
- Sphericity Imparts flow
- Porosity enhances compaction
- Highest compressibility grade and high flowability
- Significantly improved DC performance
- Retains fast disintegration
- Higher loading of active ingredients
- Effective for Formulations with Moisture-Sensitive APIs
Features:
- Provides superior binding properties and tablet ability over standard 160 µm spray-dried mannitols and other excipients
- 160 µm particle size matches typical APIs and industry-standard excipients
- Offers better disintegration time per hardness than the leading spray-dried mannitol, even under higher drug load
- Ideal for use as a base for ordered mixing with micronized APIs and low-dose formulations due to higher surface area
- Yields tablets with higher hardness and tensile strength and lower friability than standard spray-dried mannitol at comparable compression forces
Compendial USP/NF mannitol
| Available Products | Product Details |
| Mannogem® Onyx | ~50 PSD D50 (μm) |
| Mannogem® Emerald | ~25 PSD D50 (μm) |
| Mannogem® XL | ~140 PSD D50 (μm) |
| Mannogem® Granular | ~480 PSD D50 (μm) |
| Mannogem® 2080 | ~320 PSD D50 (μm) |
| Mannogem® XL Opal | 160 µm |
| Mannogem® XL Ruby | 300 µm |
