Comprecel® MCC is a Microcrystalline Cellulose derived from nature’s most abundant and renewable raw material; wood pulp. Strong dry binders with excellent compressibility that allows for high tablet hardness at low force.
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Comprecel® MCC is a Microcrystalline Cellulose derived from nature’s most abundant and renewable raw material; wood pulp. It is purified and depolymerized through an acid hydrolysis process that turns the pulp from a fibrous material to a white freely-flowing powder.
Widely used in tablets, capsules, granules, and powdered products due to its strong binding properties with high dilution potential. Comprecel is available in multiple grades to fit your application needs. Visit the chart at the bottom of this page to determine what grade is right for you or request a sample.
Superior Performance
Compared to other comparative products on the market, Comprecels:
To help you choose the right Comprecel, based on your applications here is a chart of specifications
Type | LOD% | Bulk Density g/ml | Particle Size Distribution | When to Use | ||||
---|---|---|---|---|---|---|---|---|
D10(um) | D50(um) | D90(um) | ||||||
M101 | NMT 7.0 | 0.26-0.34 | <30 | 45-75 | >110 | The standard with finer particle size. Provides superior Binding, excellent tablet hardness, and low friability. Suitable for wet granulation, roller compaction, direct compression, and spherization. | ||
M102 | NMT 7.0 | 0.28-0.35 | <50 | 90-140 | >170 | The workhorse grade, this standard has a coarser particle size than the M101 with better flowability and is best suited for direct compression. | ||
M103 | NMT 3.0 | 0.26-0.34 | <30 | 45-75 | >110 | Similar particle size to M101 but with lower moisture content – suitable when using water-sensitive active ingredients. | ||
M105 | NMT 7.0 | 0.20-0.30 | <15 | 17-27 | >35 | Finest particle size making it the most compressible of MCC grades. Helps achieve smoother texture in chewable tablets without compromising taste. Can be mixed with other grades to achieve specific flow and compressibility targets or with poorly compressible excipients such as dibasic Calcium Phosphate. For use in roller compaction and direct compression to enhance tablet hardness or for APIs with high crystallinity. | ||
M112 | NMT 1.5 | 0.28-0.37 | <50 | 90-140 | >170 | Coarser particle size, and extremely low moisture content for use with ingredients that are sensitive to moisture such as APIs, pre- and probiotics, and vitamins. | ||
M113 | NMT 2.0 | 0.26-0.34 | <30 | 45-75 | >110 | Finer particle size, and with an extremely low moisture content for use with moisture-sensitive active ingredients. | ||
M200 | NMT 7.0 | 0.32-0.42 | <85 | 150-280 | >310 | The coarsest of MCC grades providing excellent flowability facilitating high-speed tableting and low weight variation for DC, hard capsules, and in dry and wet granulation to enhance compressibility. | ||
M212 | NMT 7.0 | 0.30-0.36 | <80 | 140-180 | >250 | Mid-range particle size provides great binding and flowability to direct compression with outstanding content uniformity. | ||
M301 | NMT 7.0 | 0.34-0.45 | <30 | 45-75 | >110 | A finer particle size with higher bulk density designed for use with low-density ingredients in thinner tablets. Suitable for DC and will provide less tablet variation at higher speeds. Improves production efficiencies by allowing larger batch size. | ||
M302 | NMT 7.0 | 0.35-0.46 | <50 | 90-140 | >170 | A coarser particle size with higher bulk density designed for use with low-density ingredients in thinner tablets. Suitable for DC and will provide less tablet variation at higher speeds. Improves production efficiencies by allowing larger batch size. |
Understanding the Effects of Particle Size to better understand how your ingredient choice affects manufacturing and Product quality.
Looking for an even more enhanced flowability solution, Take a look at Comprecel SMCC.
*EFSA, Food Additive #: E460i
Comprecel® MCC is a Microcrystalline Cellulose derived from nature’s most abundant and renewable raw material; wood pulp. Strong dry binders with excellent compressibility that allows for high tablet hardness at low force.